Aptagen, LLC
DNA
HIV reverse transcriptase (HIV RT)
Cells
0.38 nM (reported value)
20 mM Tris-HCl [pH 7.4], 140 mM NaCl, 5 mM KCl, 1 mM MgCl2, and 1 mM CaCl2
25°C
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
HIV-RT 3.17 (ID# 7160)
5'dTpdTpdApdTpdGpdTpdApdGpdCpdApdTpdTpdTpdApdTpdGpdApdApdApdTpdTpdTpdTpdTpdApdApdApdTpdCpdApdApdTpdTpdTpdApdCpdTpdApdTpdTpdGpdGpdTpdGpdGpdTpdApdTpdCpdCp3'
50
15383.1 g/mole
491500 L/(mole·cm)
24.00%
2.03
31.30
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Dunn MR, McCloskey CM, Buckley P, Rhea K, Chaput JC. Generating Biologically Stable TNA Aptamers that Function with High Affinity and Thermal Stability. J Am Chem Soc. 2020 Apr 29;142(17):7721-7724. doi: 10.1021/jacs.0c00641. Epub 2020 Apr 20. PMID: 32298104.
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