Aptagen, LLC
DNA
PD-L1
Protein
441 nM (reported value)
136 mM NaCl, 2.6 mM KCl, 4 mM Na2HPO4, 1.8 mM KH2PO4, 2 mM MgCl2, pH 7.4
37°C
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
N5 (ID# 7137)
5’dGpdApdTpdTpdGpdApdGpdTpdApdGpdApdTpdApdGpdTpdGpdGpdTpdTpdCpdTpdGpdTpdApdCpdGpdTpdApdGpdTpdGpdApdApdApdGpdApdGpdTpdGpdGp3’
40
12550.2 g/mole
414300 L/(mole·cm)
42.50%
2.41
30.29
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Li, X., Li, Z., & Yu, H. (2020). Selection of threose nucleic acid aptamers to block PD-1/PD-L1 interaction for cancer immunotherapy. Chemical Communications. doi:10.1039/d0cc06032a
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