Aptamer Details

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SARS-CoV-2 Aptamer 1C (ID# 7058)

Aptamer Chemistry: DNA Target: RBD of the Spike glycoprotein from SARS-CoV-2 Antigen/Target Category: Protein Affinity (Kd): 5.8 nM (reported value) Binding Conditions/Buffer: PBS Binding Temp: °C Refolding Protocol: 95C->4C->25C Comments:

Sequence (): 5’dCpdApdGpdCpdApdCpdCpdGpdApdCpdCpdTpdTpdGpdTpdGpdCpdTpdTpdTpdGpdGpdGpdApdGpdTpdGpdCpdTpdGpdGpdTpdCpdCpdApdApdGpdGpdGpdCpdGpdTpdTpdApdApdTpdGpdGpdApdCpdAp3’ Length: 51 Molecular Weight: 15787.2 g/mole Extinction Coefficient: 482900 L/(mole·cm) GC Content: 56.86% nmoles/OD₂₆₀: 2.07 μg/OD₂₆₀: 32.69

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference:

Song, Yanling; Song, Jia; Wei, Xinyu; Huang, Mengjiao; Sun, Miao; Zhu, Lin; et al. (2020): Discovery of Aptamers Targeting Receptor-Binding Domain of the SARS-CoV-2 Spike Glycoprotein. ChemRxiv. Preprint. https://doi.org/10.26434/chemrxiv.12053535.v2 Song, Y., Song, J., Wei, X., Huang, M., Sun, M., Zhu, L., Lin, B., Shen, H., Zhu, Z., and C. Yang. 2020. Discovery of Aptamers Targeting the Receptor-Binding Domain of the SARS-CoV‑2 Spike Glycoprotein. Analytical Chemistry 2020, 92, 9895−9900. https://dx.doi.org/10.1021/acs.analchem.0c01394

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Aptamer Details

SARS-CoV-2 Aptamer 1C (ID# 7058)

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