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Aptamer Details

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Acetylcholine Receptor Antibody (mAB198) (SE RNA VII) (ID# 67)

Acetylcholine Receptor Antibody (mAB198) (SE RNA VII)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
2'-NH2-RNA Acetylcholine Receptor Antibody (mAB198) Protein 60 nM (reported value) Binding Buffer (30mM Tris-HCl (pH 7.5), 150 mM NaCl, 10mM MgCl2, 2mM dithiothreitol, 1% BSA) N/A°C NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
5'nUprGprGprGpnCpnCprGprGprAprGprGpnUpnUprAprGpnCpnUpnUprGpnCpnCpnCprApnUprGprGpnCprAprAprGpnCprAprGprGprGpnCprGpnCpnCprApnCprGprGprApnCpnCpnCprAp3' 48 28339.52 g/mole 455500 L/(mole·cm) 68.75% 2.20 62.22

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Lee, Seong-Wook and Sullenger, Bruce. "Isolation of a nuclease-resistant decoy RNA that can protect human acetylcholine receptors from myasthenic antibodies." Nature Biotechnology, 15 (1997): 41-45.

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