Aptagen, LLC
DNA
Hepatitis C Virus RdRp
Protein
1.3 nM (reported value)
Binding buffer: HEPES-buffered saline containing 1 mM CaCl2, 2.7 mM MgCl2, and 0.005% surfactant P-20 (HBS-CKM)
RT°C
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Hepatitis C Virus RdRp (r10/43) (ID# 59)
5'dGpdGpdGpdApdGpdApdCpdApdApdGpdApdApdTpdApdApdApdCpdGpdCpdTpdCpdApdApdGpdGpdGpdCpdGpdTpdGpdGpdTpdGpdGpdGpdTpdGpdGpdGpdGpdTpdApdCpdTpdApdApdTpdApdApdTpdGpdTpdGpdCpdGpdTpdTpdTpdGpdTpdTpdCpdGpdApdCpdApdGpdGpdApdGpdGpdCpdTpdCpdApdCpdApdApdCpdApdGpdGpdCp3'
83
25933.89 g/mole
827900 L/(mole·cm)
53.01%
1.21
31.32
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Jones et al. "High-Affinity Aptamers to Subtype 3a Hepatitis C Virus Polymerase Display Genotypic Specificity." Antimicrobial Agents and Chemotherapy, 50 (2006): 3019-3027.
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