Aptamer Details

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TGF-??1 (T18_1_3) (ID# 58)

TGF-??1 (T18_1_3)
DNA Transforming Growth Factor-??1 (TGF-??1) Protein 94 nM (reported value) PBS with 1 MgCl2. RT°C NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
5'dCpdGpdCpdTpdCpdGpdGpdCpdTpdTpdCpdApdCpdGpdApdGpdApdTpdTpdCpdGpdTpdGpdTpdCsdGpdTpdTpdGpdTpdGpdTpdCsdCsdTpdGpdTpdAsdCsdCsdCsdGpdCsdCsdTpdTpdGpdAsdCsdCsdAsdGpdTpdCsdAsdCsdTpdCsdTpdAsdGpdAsdGpdCsdAsdTpdCsdCsdGpdGpdAsdCsdTpdGp3' 74 23064.62 g/mole 673000 L/(mole·cm) 58.11% 1.49 34.27

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Kang, Jonghoon, et al. "Combinatorial selection of a single stranded DNA thioaptamer targeting TGF-??1 protein." Bioorganic & Medicinal Chemistry Letters, 18 (2008): 1835-1839.

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