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Aptamer Details

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HIV-1 TAR RNA Hairpin Loop (B22-19) (ID# 56)

HIV-1 TAR RNA Hairpin Loop (B22-19)
DNA HIV-1 TAR RNA Hairpin Loop Small Organic 50 nM (reported value) R buffer (20 mM HEPES (pH 7.4), 140 mM potassium acetate, 20 mM sodium acetate, 3 mM magnesium acetate) RT°C NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
5'dCpdCpdCpdTpdApdGpdTpdTpdApdGpdCpdCpdApdTpdCpdTpdCpdCpdCp3' 19 5659.71 g/mole 166500 L/(mole·cm) 57.89% 6.01 33.99

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Sekkai et al. "In Vitro Selection of DNA Aptamers Against the HIV-1 TAR RNA Hairpin." Antisense and Nucleic Acid Drug Development, 12 (2002): 265-274.

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