Aptamer Details

Periostin Aptamer (PNDA-3) (ID# 530)

Periostin Aptamer (PNDA-3)
RNA Periostin Protein 1.07 nM (reported value) 40 mM/1 HEPES, 102 mM/1 NaCl, 5 mM/1mol/1g Cl2,5 mM KCl 37°C NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding. 5' benzylaminocarbonyl-d U modification
154 15666.2 g/mole 483400 L/(mole·cm) 52.94% 2.07 32.41

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Lee, Y., Kim, I., Park, S., Kim, Y., Wu, S., Lee, J., Noh, D., Kim, K., Ryu, S. and Suh, P. "Periostin-binding DNA aptamer inhibits breast cancer growth and metastasis." The American Society of Gene & Cell Therapy 21.5 (2013): 1004-13.

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