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Aptamer Details

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L-Selectin (LD201) (ID# 49)

L-Selectin (LD201)
DNA L-Selectin Protein 1.8 nM (reported value) Binding Buffer (20 mM Hepes (pH 7.5), 125 mM NaCl, 1 mM CaCl2, 1 mM MgCl2, 5 mM KCl) plus 0.01% (wt/vol) human serum albumin. 22°C NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
5'dCpdTpdApdCpdCpdTpdApdCpdGpdApdTpdCpdTpdGpdApdCpdTpdApdGpdCpdCpdApdApdGpdGpdTpdApdApdCpdCpdApdGpdTpdApdCpdApdApdGpdGpdTpdGpdCpdTpdApdApdApdCpdGpdTpdApdApdTpdGpdGpdCpdTpdTpdCpdGpdGpdCpdTpdTpdApdCpdTpdCpdTpdCpdApdTpdGpdTpdApdGpdTpdTpdCpdCp3' 79 24243.79 g/mole 754700 L/(mole·cm) 46.84% 1.33 32.12

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Hicke, Brain, et al. "DNA Aptamers Block L-Selectin Function In Vivo Inhibition of Human Lymphocyte Traf?cking in SCID Mic." Journal of Clinical Investigation, 98 (1996): 2688-2692.

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