Aptagen, LLC
DNA
HIV-1 RT
Protein
1.1 nM (reported value)
50 mM Tris-HCl, pH 8.0, 80 mM KCl, 6 mM MgCl2, and 1 mM DTT.
RT°C
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
HIV-1 Reverse Transcriptase (R1T) (ID# 417)
5' dCpdGpdCpdCpdTpdGpdApdTpdTpdAp dGpdCpdGpdApdTpdApdCpdTpdCpdAp dGpdGpdCpdGpdTpdTpdGpdGpdGpdTp dGpdGpdGpdTpdGpdGpdGpdTpdGpdGp dGp3'
42
12825.34 g/mole
390800 L/(mole·cm)
63.41%
2.56
32.82
D Michalowski et al. Novel bimodular DNA aptamers with guanosine quadruplexes inhibit phylogenetically diverse HIV-1 reverse transcriptases. Nucleic Acid Res. 36(2008): 7124-7135.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
D Michalowski et al. Novel bimodular DNA aptamers with guanosine quadruplexes inhibit phylogenetically diverse HIV-1 reverse transcriptases. Nucleic Acid Res. 36(2008): 7124-7135.
Y-T Lai and J DeStefano. DNA aptamers to human immunodeficiency virus reverse transcriptase selected by a primer-free SELEX method: characterization and comparison with other aptamers. Nucleic Acid Therapeutics 22(2012): 162-176.
Have your aptamer oligo synthesized ORDER NOW
We are always looking for ways to improve. Please tell us what you think.