Aptagen, LLC
DNA
L-Selectin binding to sialyl Lewis X
Protein
3 nM (reported value)
Binding Buffer (20 mM Hepes, 111 mM NaCl, 1 mM CaCl2, 1 mM MgCl2, 5 mM KCl, 8.9 mM NaOH final pH 8) and 1% globulin-free BSA.
22°C
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
L-Selectin (LD201t1) (ID# 407)
5'dTpdApdGpdCpdCpdApdApdGpdGpdTpdApdApdCpdCpdApdGpdTpdApdCpdApdApdGpdGpdTpdGpdCpdTpdApdApdApdCpdGpdTpdApdApdTpdGpdGpdCpdTpdTpdCpdGpdGpdCpdTpdTpdApdCp3'
49
15113.89 g/mole
481400 L/(mole·cm)
46.94%
2.08
31.40
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Hicke, Brain, et al. "DNA Aptamers Block L-Selectin Function In Vivo Inhibition of Human Lymphocyte Traf?cking in SCID Mic." Journal of Clinical Investigation, 98 (1996): 2688-2692
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