Aptagen, LLC
RNA
HIV-1 Tat protein
Protein
120 pM (reported value)
Binding Buffer: 50 mM Tris-HCl (pH 7.8) and 50 mM KCl
r.t.°C
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
HIV-1 Tat protein (ID# 364)
5' rAprCprGprAprAprGprCprUprUprGp rAprUprCprCprCprGprUprUprUprGp rCprCprGprGprUprCprGprAprUprCp rGprCprUprUprCprGprAp3'
38
11784.08 g/mole
352600 L/(mole·cm)
56.76%
2.84
33.42
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
R Yamamoto et al. A novel RNA motif that binds efficiently and specifically to the Tat protein of HIV and inhibits the trans-activation by Tat of transcription in vitro and in vivo. Genes to Cells 5(2000):371-388
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