Aptagen, LLC
DNA
?1-Adrenoceptor Autoantibodies(AABs)
Protein
n/a nM (reported value)
Buffer 1: Tris buffer pH 7.3, 0.1% Tween-20, DMEM, 0.1% Tween-20 Buffer 2: Phosphate buffer pH 7.5, 0.1% Tween-20
N/A°C
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Low affinity aptamers were removed from the column using both buffers.
Anti -?1-Adrenergic Receptor-Autoantibodies (Aptamer 110) (ID# 274)
5'dApdCpdApdGpdTpdApdApdCpdCpdGpdCpdGpdTpdGpdApdGpdGpdTpdCpdGpdAp3'
21
6480.27 g/mole
212600 L/(mole·cm)
57.14%
4.70
30.48
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Haberland, A., et al. "Aptamer Neutralization of Beta1-Adrenoceptor Autoantibodies Isolated From Patients With Cardiomyopathies." Circulation Research, 109 (2011): 986-992.
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