Aptagen, LLC* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.Peptide Thrombopoietin Receptor Protein 2 nM (reported value) N/A NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding. The authors also created a dimerized version of AF12505 (AF13948). This peptide aptamer possessed an IC50 of 0.5 nM and EC50 4000 times that of the monomer.