Aptagen, LLC
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
2'-NH2-RNA
Anti-acetylcholine Autoantibodies
Protein
60 nM (reported value)
Binding Buffer (30 mM Tris-HCl (pH 7.5), 150 mM NaCl, 10 mM MgCl2, 2 mM DTT, 1% BSA)
N/A°C
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Anti-acetylcholine Autoantibodies (SE RNA) (ID# 133)
5'nUprGprGprGpnCpnCprGprGprAprGprGpnUpnUprAprGpnCpnUpnUprGpnCpnCpnCprApnUprGprGpnCprAprAprGpnCprAprGprGprGpnCprGpnCpnCprApnCprGprGprApnCpnCpnCprAp3'
48
28339.52 g/mole
455500 L/(mole·cm)
68.75%
2.20
62.22
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Lee and Sullenger. "Isolation of a nuclease-resistant decoy RNA that can protect human acetylcholine receptors from myasthenic antibodies." Nature Biotechnology, 15(1997):
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