Aptamer Details

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R10X4 (ID# 9609)

Aptamer Chemistry: DNA

Target: Xanthine

Antigen/Target Category: Other

Affinity (Kd): 12.5 µM (reported value)

Binding Temp: 75.7°C

Refolding Protocol: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.

Sequence ():

Length: 36

Molecular Weight: 11181.3

Extinction Coefficient: 351500

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference:

Ding Y, Gu L, Wang X, Zhang Z, Zhang H, Liu J. Affinity-Guided Coevolution of Aptamers for Guanine, Xanthine, Hypoxanthine, and Adenine. ACS Chem Biol. 2024 Jan 19;19(1):208-216. doi: 10.1021/acschembio.3c00660. Epub 2024 Jan 9. PMID: 38194356.

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