Aptagen, LLC
RNV95 (ID# 9529)
DNA
ABeta40
Small Organic
150-200 nM (reported value)
85.1°C
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
5'-dApdCpdApdApdApdGpdCpdGpdApdCpdApdCpdApdCpdApdGpdGpdApdGpdCpdCpdTpdGpdGpdGpdGpdGpdGpdCpdGpdGpdApdCpdGpdApdTpdApdGpdGpdGpdGpdCpdCpdCpdCpdCpdCpdGpdGpdTpdApdGpdGpdApdTpdGpdGpdApdCpdGpdGpdGpdApdCpdApdGpdGpdApdCpdCpdApdCpdApdCpdCpdCpdApdGpdCpdGp-3'
80
24878.1 g/mole
786200 L/(mole·cm)
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Chakravarthy M, H Alshamaileh, H Huang, RK Tannenberg, S Chen, S Worrall, PR Dodd and RN Veedu. (2018). Development of DNA aptamers targeting low-molecularweight amyloid-b peptide aggregates: in vitro. Chem Commun 54:4593–4596. DOI https://doi.org/10.1039/C8CC02256A
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