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Apta-Index™: Adenine (12E4) (ID# 96)

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Adenine (12E4) (ID# 96)

Adenine (12E4)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
RNA Adenine Small Organic 10 nM (reported value) Binding Buffer: 100 mM HEPES, 500 mM NaCl, 5 mM MgCl2 (pH 7.3) N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
5'-rGprGprGprAprGprAprGprGprAprUprAprCprUprAprCprAprCprGprUprGprAprUprAprGprGprAprCprGprAprUprUprAprUprCprGprAprAprAprAprUprCprAprCprCprAprGprAprUprUprGprGprAprCprCprCprUprGprGprUprUprAprAprCprGprAprUprCprCprAprUprUprGprCprAprUprGprUprAprGprCprAprGprAprAprGprCprUprUprCprCprGp-3'
91 29362.78 g/mole 927600.00 L/(mole·cm) 47.25% 1.08 31.65

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Meli, M., et al. "Adenine-aptamer complexes: a bipartite RNA site that binds the adenine nucleic base." Journal of Biological Chemistry, 227 (2001): 2104-2111.

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