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Apta-Index™: Cholic Acid (9) (ID# 94)

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Cholic Acid (9) (ID# 94)

Cholic Acid (9)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
DNA Cholic Acid Small Organic 50 pM (reported value) selection buffer (50 mM Tris–HCl, 300 mM NaCl, 30 mM KCl, 5 mM MgCl2, pH 7.6 N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
5'-dGpdTpdApdCpdCpdApdGpdCpdTpdTpdApdTpdTpdCpdApdApdTpdTpdApdCpdCpdGpdCpdGpdApdApdGpdApdApdGpdTpdGpdTpdCpdApdTpdTpdGpdTpdTpdTpdTpdGpdGpdApdGpdApdTpdTpdCpdGpdApdApdGpdCpdGpdCpdTpdGpdTpdApdCpdApdCpdApdGpdGpdTpdApdApdTpdGpdApdApdGpdCpdCpdTpdTpdCpdTpdApdApdGpdApdTpdApdGpdTpdApdTpdGpdTpdTpdCpdApdTpdCpdApdGp-3'
100 30924.20 g/mole 985700.00 L/(mole·cm) 41.00% 1.01 31.37

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Kato, T., et al. "In vitro selection of DNA aptamers which bind to cholic acid." Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 1493 (2000):

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