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Apta-Index™: Receptor Tyrosine Kinase (RET) Mutant (D4) (ID# 88)

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Receptor Tyrosine Kinase (RET) Mutant (D4) (ID# 88)

Receptor Tyrosine Kinase (RET) Mutant (D4)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
2'-F-RNA Receptor Tyrosine Kinase (RET) Mutant Protein 35 nM (reported value) Selection buffer: RPMI 1640 N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
5'-rGpfCprGpfCprGprGprGprAprApfUprAprGpfUprApfUprGprGprAprAprGprGprApfUprApfCprGpfUprApfUprApfCpfCprGpfUprGpfCprAprApfUpfCpfCprAprGprGprGpfCprAprApfCprGp-3'
50 16281.84 g/mole 511900.00 L/(mole·cm) 54.00% 1.95 31.81

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Cerchia, Laura, et al. "Neutralizing Aptamers from Whole-Cell SELEX Inhibit the RET Receptor Tyrosine Kinase." PLoS Biology, 3 (2004): e123

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