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Apta-Index™: Methylenedianiline (M1) (ID# 81)

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Methylenedianiline (M1) (ID# 81)

Methylenedianiline (M1)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
RNA Methylenedianiline Small Organic 450 nM (reported value) Binding buffer: 250 mM NaCl, 50 mM Tris–HCl, 5 mM MgCl2 N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
5'-rGprGprGprAprGprAprCprAprAprGprAprAprUprAprAprAprCprGprCprUprCprAprAprCprUprGprCprGprAprUprCprAprGprGprGprGprUprAprAprAprUprUprUprCprCprGprCprGprCprAprGprGprCprUprCprCprAprCprGprCprCprGprCprUprUprCprGprAprCprAprGprGprAprGprGprCprUprCprAprCprAprAprCprAprGprGprCp-3'
87 28102.08 g/mole 852400.00 L/(mole·cm) 57.47% 1.17 32.97

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Brockstedt, U., et al. "In vitro evolution of RNA aptamers recognizing carcinogenic aromatic amines." Biochemical and Biophysical Research Communications, 313 (2004): 1004-1008.

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