Aptagen, LLC
RNA
Amyloid Peptide BetaA4(1ƒ?? 40)
Peptide
29 nM (reported value)
Binding Buffer (10 mM Trisƒ??HCl (pH 7.5), 150 mM NaCl, 5 mM MgCl2, 1 mM EDTA). Incubated at room temperature.
N/A°C
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
This aptamer is specific to polymeric amyloid.
Amyloid Peptide BetaA4(1ƒ?? 40) (B55) (ID# 70)
5'rGprGprGprAprAprUprUprCprGprAprGprCprUprCprGprGprUprAprCprCprUprUprUprAprCprCprGprUprAprAprGprGprCprCprUprGprUprCprUprUprCprGprUprUprUprGprAprCprAprGprCprGprGprCprUprUprGprUprUprGprAprCprCprCprUprCprAprCprAprCprUprUprUprGprUprAprCprCprUprGprCprUprGprCprCprAprAprCprUprGprCprAprGprGprCprAprUprGprCprAprAprGprCprUprUprGprGp3'
107
34199.41 g/mole
1012800 L/(mole·cm)
54.21%
0.99
33.77
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Ylera, Francisco, et al. "Selection of RNA Aptamers to the Alzheimer's Disease Amyloid Peptide." Biochemical and Biophysical Research Communities, 290 (2002): 1583-1588.
Have your aptamer oligo synthesized ORDER NOW
We are always looking for ways to improve. Please tell us what you think.