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Apta-Index™: Aptamer M3 (ID# 647)

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Aptamer M3 (ID# 647)

Aptamer M3
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
DNA BC MDA-MB-231 Cells 45.6 nM (reported value) PBS N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
5'-dApdApdGpdGpdApdGpdCpdApdGpdCpdGpdTpdGpdGpdApdGpdGpdApdTpdApdTpdApdCpdApdCpdCpdGpdTpdCpdApdTpdCpdApdGpdApdGpdGpdGpdApdGpdCpdApdTpdCpdTpdCpdTpdApdGpdTpdCpdApdGpdGpdApdCpdTpdGpdTpdGpdApdTpdGpdApdApdTpdTpdApdGpdGpdGpdTpdGpdTpdGpdTpdCpdGpdTpdCpdGpdTpdGpdGpdTp-3'
85

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Li, W., Zhou, L., Zheng, M., & Fang, J. (2018). Selection of Metastatic Breast Cancer Cell-Specific Aptamers for the Capture of CTCs with a Metastatic Phenotype by Cell-SELEX. Molecular Therapy - Nucleic Acids,12, 707-717. doi:10.1016/j.omtn.2018.07.008

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