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Apta-Index™: Antibac 2 (ID# 625)

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Antibac 2 (ID# 625)

Antibac 2
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
DNA peptidoglycan Other 195.90 nM (reported value) Selection buffer (PBS containing 1.4 mM MgCl2 and 0.05% BSA); Room temperature (45 mins) N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding. Antibac 2 was tested on A. baumanni, L. monocitogenes, E. coli, S. aureus, and K. pneumonia, among others. The Kd listed above is for K. Pneumonia.
5'-dTpdCpdGpdCpdGpdCpdGpdApdGpdTpdCpdGpdTpdCpdTpdGpdGpdGpdGpdGpdApdCpdTpdApdGpdApdGpdGpdApdCpdTpdTpdGpdTpdGpdCpdGpdGpdCpdCpdCpdCpdGpdCpdApdTpdCpdGpdTpdCpdCpdTpdCpdCpdCp-3'
55 16912.91 g/mole 497500.00 L/(mole·cm) 69.09% 2.01 34.00

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

A Graziani et al. High efficiency binding aptamers for a wide range of sepsis 1 bacterial agents. JMB Papers in Press. 2017: JMB16-11004.

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