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Apta-Index™: HER3 (A30) (ID# 62)

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HER3 (A30) (ID# 62)

HER3 (A30)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
RNA HER3 Protein 45 nM (reported value) Binding buffer: 10 mM HEPES (pH 7.4), 100 mM NaCl, and 2.5 mM MgCl2 N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
5'-rGprAprAprUprUprCprCprGprCprGprUprGprUprGprCprCprAprGprCprGprAprAprAprGprUprUprGprCprGprUprAprUprGprGprGprUprCprAprCprAprUprCprGprCprAprGprGprCprAprCprAprUprGprUprCprAprUprCprUprGprGprGprCprGprGprUprCprCprGprUprUprCprGprGprGprAprUprCprCp-3'
79 25442.28 g/mole 761100.00 L/(mole·cm) 59.49% 1.31 33.43

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Chi-Hong et al. "Inhibition of heregulin signaling by an aptamer that preferentially binds to the oligomeric form of human epidermal growth factor receptor-3." Proceedings of the National Academy of Sciences of the United States of America 100,(2003):9226-9231.

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