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Apta-Index™: PAI-1 01 (ID# 612)

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PAI-1 01 (ID# 612)

PAI-1 01
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
DNA Plasminogen Activator Inhibitor-1 Protein 339 pM (reported value) PBSMCT (DPBS with 2.5 mM MgCl2, 1 mM CaCl2, 0.05% TWEEN-20) N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
5'-dCpdApdTpdTpdGpdApdGpdApdTpdApdGpdCpdTpdApdGpdTpdTpdGpdTpdApdGpdCpdTpdGpdCpdGpdTpdCpdApdTpdApdGpdGpdCpdTpdGpdGpdGpdTpdTpdGpdGpdGpdTpdCpdTpdApdGpdTpdGpdGpdTpdTpdGpdGpdGpdTpdGpdTpdGp-3'
60 18766.23 g/mole 579300.00 L/(mole·cm) 51.67% 1.73 32.39

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Wang, J., Gong, Q., Maheshwari, N., Eisenstein, M., Luz Arcila, M., Kosik, K., & Soh, T. Particle Display: A Quantitative Screening Method for Generating High-Affinity Aptamers. Angew. Chem. Int. Ed. 2014, 53, 4796–4801

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