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Apta-Index™: Z23 Anti-Vesicular Stomatitis Virus (ID# 606)

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Z23 Anti-Vesicular Stomatitis Virus (ID# 606)

Z23 Anti-Vesicular Stomatitis Virus
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
DNA Vesicular Stomatitis Virus Other EC50 =/< 80 nM (reported value) 90% High Glucose DMEM, 10% Fetal Bovine Serum. Tested in vivo. N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
5'-dGpdGpdGpdApdCpdCpdTpdApdTpdCpdApdGpdGpdCpdGpdApdTpdGpdTpdGpdApdApdApdApdCpdTpdCpdTpdTpdApdTpdApdCpdCpdApdCpdTpdGpdGp-3'
39 12015.87 g/mole 380500.00 L/(mole·cm) 48.72% 2.63 31.58

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Muharemagic D, Zamay A, Ghobadloo SM, Evgin L, Savitskaya A, et al. (2014) Aptamer-Facilitated Protection of Oncolytic Virus from Neutralizing Antibodies. Molecular Therapy--Nucleic Acids 3, e167. doi: 10.1038/mtna.2014.19

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