Aptagen, LLC
DNA
Vesicular Stomatitis Virus
Other
EC50 =/< 80 nM (reported value)
90% High Glucose DMEM, 10% Fetal Bovine Serum. Tested in vivo.
37°C
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Z23 Anti-Vesicular Stomatitis Virus (ID# 606)
5'dGpdGpdGpdApdCpdCpdTpdApdTpdCpdApdGpdGpdCpdGpdApdTpdGpdTpdGpdApdApdApdApdCpdTpdCpdTpdTpdApdTpdApdCpdCpdApdCpdTpdGpdGp3'
39
12015.87 g/mole
380500 L/(mole·cm)
48.72%
2.63
31.58
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Muharemagic D, Zamay A, Ghobadloo SM, Evgin L, Savitskaya A, et al. (2014) Aptamer-Facilitated Protection of Oncolytic Virus from Neutralizing Antibodies. Molecular Therapy--Nucleic Acids 3, e167. doi: 10.1038/mtna.2014.19
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