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Apta-Index™: Hepatitis C Virus RdRp (r10/43) (ID# 59)

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Hepatitis C Virus RdRp (r10/43) (ID# 59)

Hepatitis C Virus RdRp (r10/43)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
DNA Hepatitis C Virus RdRp Protein 1.3 nM (reported value) Binding buffer: HEPES-buffered saline containing 1 mM CaCl2, 2.7 mM MgCl2, and 0.005% surfactant P-20 (HBS-CKM) N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
5'-dGpdGpdGpdApdGpdApdCpdApdApdGpdApdApdTpdApdApdApdCpdGpdCpdTpdCpdApdApdGpdGpdGpdCpdGpdTpdGpdGpdTpdGpdGpdGpdTpdGpdGpdGpdGpdTpdApdCpdTpdApdApdTpdApdApdTpdGpdTpdGpdCpdGpdTpdTpdTpdGpdTpdTpdCpdGpdApdCpdApdGpdGpdApdGpdGpdCpdTpdCpdApdCpdApdApdCpdApdGpdGpdCp-3'
83 25933.89 g/mole 827900.00 L/(mole·cm) 53.01% 1.21 31.32

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Jones et al. "High-Affinity Aptamers to Subtype 3a Hepatitis C Virus Polymerase Display Genotypic Specificity." Antimicrobial Agents and Chemotherapy, 50 (2006): 3019-3027.

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