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Apta-Index™: Botulinum neurotoxin type A (BoNT A) Aptamer (S132B-C22) (ID# 528)

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Botulinum neurotoxin type A (BoNT A) Aptamer (S132B-C22) (ID# 528)

Botulinum neurotoxin type A (BoNT A) Aptamer (S132B-C22)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
DNA BoNT A Light Chain Protein 87 nM (reported value) PBS pH 7.4, 300 mM NaCl, 3mM MgCl2, 5mM DTT, 1mg/ml BSA, 0.2 % Tween, 1mg/ml heparin None Aptamer was developed to inhibit endopeptidase activity of BoNT A.
dGpdGpdGpdApdGpdGpdApdGpdGpdApdGpdApdGpdApdTpdGpdTpdGpdApdApdCpdTpdTpdGpdApdCpdApdGpdCpdGpdTpdGpdCpdCpdTpdApdGpdApdApdGpdTpdCpdCpdApdApdGpdCpdTpdTpdApdApdApdTpdApdApdCpdCpdApdCpdGpdCpdTpdCpdGpdApdCpdApdApdGpdCpdApdGpdApdApdApdCpdTpdCpdTpdApdCpdApdCpdTpdGpdGpdApdCpdTpdGpdGpdCpdGp
93 28858.79 g/mole 924400.00 L/(mole·cm) 51.61% 1.08 31.22

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Chang, T., Blank, M., Janardhanan, P., Singh, B., Mello, C., Blind, M., Cai, S. "In vitro selection of RNA aptamers that inhibit the activity of type A botulinum neurotoxin." Biochemical and Biophysical Research Communications 396(2010): 854-860.

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