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Apta-Index™: Estrogen Aptamer (AptER-1) (ID# 517)

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Estrogen Aptamer (AptER-1) (ID# 517)

Estrogen Aptamer (AptER-1)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
RNA Apo-estrogen receptor alpha Protein 16 nM (reported value) 12 mM HEPES/pH 7.6, 150 mM NaCl, and 10 mM MgCl2 N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
dGpdGpdGpdCpdApdGpdApdCpdGpdCpdApdCpdCpdGpdCpdGpdApdApdCpdApdApdApdApdCpdGpdCpdApdApdGpdApdCpdApdGpdApdGpdTpdGpdCpdCpdGpdApdCpdApdApdGpdApdGpdCpdApdCpdTpdApdCpdApdApdGpdCpdTpdTpdCpdTpdGpdCpdCpdCp
65 20019.01 g/mole 635300.00 L/(mole·cm) 58.46% 1.57 31.51

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Xu, D., Chatakonda, V., Kourtidis, A., Conklin, D., and Shi, H. "In Search of Novel Drug Target Sites on Estrogen Receptors Using RNA Aptamers." Nucleic acid therapeutics 24.3 (2014): 227-38.

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