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Apta-Index™: JH6 (ID# 513)

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JH6 (ID# 513)

JH6
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
DNA NB4 AML cell line Cells 2.77 nM (reported value) 4.5 g/L glucose, 5 mM MgCl2, 0.1 mg/ml yeast tRNA and 1 mg/ml Bovine Serum Albumin (BSA) into Phosphate buffered saline (PBS) N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
dGpdApdCpdGpdCpdTpdTpdApdCpdTpdCpdApdGpdGpdTpdGpdTpdGpdApdCpdTpdCpdGpdGpdTpdApdCpdGpdCpdCpdGpdCpdApdApdGpdApdCpdGpdApdGpdTpdTpdGpdTpdGpdTpdApdTpdApdApdGpdCpdCpdGpdGpdCpdCpdGpdApdApdGpdGpdApdCpdGpdCpdApdGpdApdTpdGpdApdApdGpdTpdCpdTpdCp
78 24176.70 g/mole 757900.00 L/(mole·cm) 56.41% 1.32 31.90

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Yang, M. et al. "Developing aptamer probes for acute myelogenous leukemia detection and surface protein biomarker discovery." Journal of Hematology & Oncology 2014, 7:5.

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