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Apta-Index™: Insulin-Linked Polymorphic Region Two-Repeat (ILPR2) (ID# 499)

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Insulin-Linked Polymorphic Region Two-Repeat (ILPR2) (ID# 499)

Insulin-Linked Polymorphic Region Two-Repeat (ILPR2)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
DNA Insulin Peptide N/A nM (reported value) Tris buffer (20 mM Tris, 5mM KCL, pH 7.3) N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding. Each repeat forms a G-quartet.
5'-dApdCpdApdGpdGpdGpdGpdTpdGpdTpdGpdGpdGpdGpdApdCpdApdGpdGpdGpdGpdTpdGpdTpdGpdGpdGpdGp-3'
28 8911.82 g/mole 283900.00 L/(mole·cm) 71.43% 3.52 31.39

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Connor A C, McGown L B, et al. (2006) Insulin Capture by an Insulin-Linked Polymorphic Region G-Quadruplex DNA Oligonucleotide. J Am Chem Soc. 128: 4986-4991.

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