Aptagen, LLC
DNA
FcγrIIIα / FcgrIIIa / CD16a
Protein
22 nM (reported value)
Binding Buffer: DPBS with 0.05% BSA
37°C
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Did not bind to CD16β.
Fcγ receptor IIIα / CD16α (CLN0020) (ID# 495)
5'dGpdGpdApdGpdGpdGpdApdApdApdApdGpdTpdTpdApdTpdCpdApdGpdGpdCpdCpdApdCpdTpdGpdCpdGpdGpdGpdGpdGpdTpdCpdTpdApdTpdApdCpdGpdTpdGpdApdGpdGpdApdApdGpdApdApdGpdTpdGpdGpdGpdCpdApdGpdGpdTpdCp3'
60
18824.27 g/mole
606600 L/(mole·cm)
56.67%
1.65
31.03
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Boltz A, Plater B, Hock B, et al. (2011) Bi-specific Aptamers Mediating Tumour Cell Lysis. J Biol Chem 286: 21896-21905
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