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Apta-Index™: p-Nosyl Protected Alkyl Amino Group (M6b-M14) (ID# 459)

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p-Nosyl Protected Alkyl Amino Group (M6b-M14) (ID# 459)

p-Nosyl Protected Alkyl Amino Group (M6b-M14)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
DNA p-nosyl protected alkyl amino groups Small Organic 2.27 nM (reported value) Optimized Buffer: 10 mM Na2HPO4, 2 mM KH2, 500 mM NaCl, pH 7.4. N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding. Forms an anti-parallel G-quadruplex.
5'- dApdTpdCpdApdTpdGpdGpdTpdGpdGp dGpdTpdApdTpdCpdGpdGpdCpdApdCp dTpdCpdGpdTpdTpdGpdGpdTpdTpdGp dApdTp-3'
32 9917.50 g/mole 306300.00 L/(mole·cm) 50.00% 3.26 32.38

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Mei H et al. (2012) Functional-group specific aptamers indirectly recognizing compounds with alkyl amino group. Anal. Chem. 84: 7323 - 7329

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