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Apta-Index™: MUC1 Tumor Marker (MUC1-5TR-1) (ID# 445)

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MUC1 Tumor Marker (MUC1-5TR-1) (ID# 445)

MUC1 Tumor Marker (MUC1-5TR-1)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
DNA MUC1 recombinant protein with five repeats of the variable tandem repeat region Protein 47.3 nM (reported value) Running Buffer for SPR/Binding Buffer: 100 mM NaCl, 5 mM MgCl2, pH 7.4. N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
5'-dGpdGpdGpdApdGpdApdCpdApdApdGpdApdApdTpdApdApdApdCpdGpdCpdTpdCpdApdAp dGpdApdApdGpdTpdGpdApdApdApdApdTpdGpdApdCpdApdGpdApdApdCpdApdCpdApdApdCpdAp dTpdTpdCpdGpdApdCpdApdGpdGpdApdGpdGpdCpdTpdCpdApdCpdApdApdCpdApdGpdGpdCp -3'
72 22353.64 g/mole 748000.00 L/(mole·cm) 45.83% 1.34 29.88

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

C Ferreira et al. DNA aptamers against the MUC1 tumour marker: design of aptamer-antibody sandwich ELISA for the early diagnosis of epithelial tumors. Anal. Bioanal. Chem. 390(2008):1039-1050.

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