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Apta-Index™: Tobramycin (J6) (ID# 41)

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Tobramycin (J6) (ID# 41)

Tobramycin (J6)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
RNA Tobramycin Small Organic 2 nM (reported value) Selection Buffer: 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1mM MgCl2, and 20 mM Tris Acetate (pH 7.4) N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
5'-rGprGprGprAprGprAprAprUprUprCprCprGprAprCprCprAprGprAprAprGprCprUprUprAprGprUprAprUprAprGprCprGprAprGprGprUprUprUprAprGprCprUprAprCprAprCprUprCprGprUprGprCprUprGprAprUprCprGprUprUprUprGprGprUprAprCprGprGprGprAprCprCprUprGprCprGprUprGprUprAprGprCprCprCprAprUprAprUprGprUprGprCprGprUprCprUprAprCprAprUprGprGprAprUprCprCprUprCprAp-3'
109 35049.02 g/mole 1078300.00 L/(mole·cm) 51.38% 0.93 32.50

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Wang, Yong, et al. "Specific binding of aminoglycoside antibiotics to RNA." Chemistry & Biology 2 (1995): 281-290

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