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Apta-Index™: Platelet-Derived Growth Factor (PDGF) B-chain (36t) (ID# 372)

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Platelet-Derived Growth Factor (PDGF) B-chain (36t) (ID# 372)

Platelet-Derived Growth Factor (PDGF) B-chain (36t)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
DNA Platelet-Derived Growth Factor -BB (PDGF-BB) Protein 0.093 nM (reported value) Selection Buffer: PBSM(10.1 mM Na2HPO4, 1.8 mM K2HPO4, 137 mM NaCl and 2.7 mM KCl, 1 mM MgCl2 (pH 7.4)) N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding. Contains a terminal 3'-3'-linked thymidine residue to protect from 3' exonuclease degradation.
5'-dCpdApdCpdApdGpdGpdCpdTpdApdCpdGpdGpdCpdApdCpdGpdTpdApdGpdApdGpdCpdApdTpdCpdApdCpdCpdApdTpdGpdApdTpdCpdCpdTpdGpdTpdGpdTi-3'
40 12266.00 g/mole 382300.00 L/(mole·cm) 56.41% 2.62 32.08

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Green, L., et al. "Inhibitory DNA Ligands to Platelet-Derived Growth Factor B-Chain." Journal of Biochemistry, 35(1996): 14413-14424.

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