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Apta-Index™: Lead (Pb) binding aptamer (ID# 327)

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Lead (Pb) binding aptamer (ID# 327)

Lead (Pb) binding aptamer
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
DNA Lead (Pb) Other 1 nM (reported value) pH 7.0, 20 mM NaNO3, 8 mM Tris nitrate, 100 μM NaCN, 25 °C N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding. Aptamer forms a G-quartet in the presence of lead ions.
5'-dGpdGpdTpdTpdGpdGpdTpdGpdTpdGpdGpdTpdTpdGpdGp-3'
15 4726.13 g/mole 143300.00 L/(mole·cm) 60.00% 6.98 32.98

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

B-F Ye et al. "Colorimetric photonic hydrogel aptasensor for the screening of heavy metal ions." Nanoscale 4(2012): 5998-6003.

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