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Apta-Index™: Cyclophilin B (M9-5) (ID# 318)

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Cyclophilin B (M9-5) (ID# 318)

Cyclophilin B (M9-5)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
2'-F-RNA Cyclophilin B (CypB) pancreatic cell line Cells 1.5 nM (reported value) Buffer F: 20 mM HEPES pH 7.5, 150 mM NaCl, 2mM CaCl2, and 3 mM MgCl2 N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
5'-rGprGprGp rAprGprGp rApfCprGp rApfUprGp fCprGprGp rGprGprAp fCpfCpfUp rApfUprGp fCprAprGp fUprAprGp fCpfCprAp rGpfUprGp fUprGprGp rApfCpfUp rGprGprGp fCpfUprGp fCpfCpfCp fCpfCpfCp fCpfCprAp rGprApfCp rGprApfCp fUpfCprGp fCpfCpfCp rGprAp-3'
71 23031.81 g/mole 674400.00 L/(mole·cm) 69.01% 1.48 34.15

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Ray, P. (2012). Comparing human pancreatic cell secretomes by in vitro aptamer selection identifies cyclophilin b as a candidate pancreatic cancer biomarker. J. Clin. Invest., 122(5), 1734-1741. doi: 10.1172/JC162385

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