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Apta-Index™: HPV-HF cell line (14) (ID# 316)

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HPV-HF cell line (14) (ID# 316)

HPV-HF cell line (14)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
DNA HPV-nontumorigenic HF cell line Cells 7.1 nM (reported value) 1% BSA in PBS with salts N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding. Aptamer able to penetrate cell surface and internalized in cell cytoplasm independent of protein binding.
5'-dApdTpdAp dCpdCpdAp dGpdCpdTp dTpdApdTp dTpdCpdAp dApdTpdTp dGpdGpdGp dCpdGpdGp dGpdGpdAp dGpdTpdAp dGpdGpdGp dApdGpdAp dGpdGpdGp dGpdTpdTp dTpdCpdCp dApdTpdCp dGpdGpdCp dGpdApdCp dApdGpdAp dGpdGpdAp dGpdTpdTp dApdTpdGp dTpdGpdTp dGpdTpdAp dGpdApdTp dApdGpdTp dApdApdGp dTpdGpdCp dApdApdTp dCpdTp-3'
89 27814.14 g/mole 893700.00 L/(mole·cm) 48.31% 1.12 31.12

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Graham JC, Zarbl H (2012) Use of Cell-SELEX to Generate DNA Aptamers as Molecular Probes of HPV-Associated Cervical Cancer Cells. PLoS ONE 7(4): e36103. doi:10.1371/journal.pone.0036103

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