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Apta-Index™: Hepatitis B Virus (HBV) Polymerase (P protein) (A9) (ID# 253)

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Hepatitis B Virus (HBV) Polymerase (P protein) (A9) (ID# 253)

Hepatitis B Virus (HBV) Polymerase (P protein) (A9)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
RNA Hepatitis B Virus (HBV) Polymerase (P protein) Protein N/A nM (reported value) binding buffer (0.1 M sodium phosphate (pH 7.4), 150 mM NaCl, 20 mM imidazol, 0.1% (v/v) NP-40, 100 mg/ml yeast tRNA), 30 °C N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
5'- rUprGprUprUprCprAprUprGprUprCp rCprUprAprCprUprGprUprUprCprAp rAprAprCprAprAprAprAprAprAprAp rCprUprGprUprGprCprAprCprAprAp rAprAprAprUprAprAprAprUprUprGp rGprGprGprCprAprUprGprGprAprCp rAp-3'
61 19585.92 g/mole 626700.00 L/(mole·cm) 36.07% 1.60 31.25

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Feng et al. "A SELEX-Screened Aptamer of Human Hepatitis B Virus RNA Encapsidation Signal Suppresses Viral Replication." PLoS One, 6(2011): e27862

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