* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
Peptide EphA2 Receptor Tissue 186 nM (reported value)Blocked with 0.5% BSA in TBS and washed with binding buffer (TBS, 1 mM CaCl2, 0.1% Tween 20).N/A
If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.See also the SWL peptide that targets this protein.
NH2-TyrSerAlaTyrProAspSerValProMetMetSer-COOH
121483.71 g/mole
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Koolpe et al. "An Ephrin Mimetic Peptide That Selectively Targets the EphA2 Receptor." J. Biol. Chem., 49(2002): 46974 –4697.
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* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
Peptide
EphA2 Receptor
Tissue
186 nM (reported value)
Blocked with 0.5% BSA in TBS and washed with binding buffer (TBS, 1 mM CaCl2, 0.1% Tween 20).
N/A
If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
See also the SWL peptide that targets this protein.
