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Apta-Index™: PCB72 (Aptamer 9.3) (ID# 229)

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PCB72 (Aptamer 9.3) (ID# 229)

PCB72 (Aptamer 9.3)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
DNA Polychlorinated biphenyl 72 (PCB) Small Organic 66 nM (reported value) Binding Buffer (100 mM NaCl, 20 mM Tris–HCl, 2 mM MgCl2, 5 mM KCl, 1 mM CaCl2, pH 7.6) N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding. See also PCB106 (Aptamer 9.3).
5'-dApdGpdCp dApdGpdCp dApdCpdAp dGpdApdGp dGpdTpdCp dApdGpdAp dTpdGp dCpdApdCp dTpdCpdGp dGpdApdCp dCpdCpdCp dApdTpdTp dCpdTpdCp dCpdTpdTp dCpdCpdAp dTpdCpdCp dCpdTpdCp dApdTpdCp dCpdGpdTp dCpdCpdAp dCp dCpdCpdTp dApdTpdGp dCpdGpdTp dGpdCpdTp dApdCpdCp dGpdTpdGp dApdAp -3'
80 24336.74 g/mole 735000.00 L/(mole·cm) 57.50% 1.36 33.11

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Mehta et al. "Selection and characterization of PCB-binding DNA aptamers." Analytical Chemistry 84(2012): 1669-1676.

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