Aptagen, LLC
RNA
Hemagglutinin of the Subtype H5 Avian Influenza Virus
Protein
N/A nM (reported value)
Wash Buffer (PBS Buffer (pH 7.4), 140 mM NaCl, and 2.7 mM KCl)
RT°C
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
This aptamer binds to the hemagglutinin receptor-binding domain and suppresses RBC agglutination.
H5 Avian Influenza Virus (HAS15-5) (ID# 226)
5'rGprGprGprUprUprCprAprCprUprGprCprAprGprAprCprUprUprGprAprCprGprAprAprGprCprUprUprAprCprAprAprAprCprAprAprGprAprGprCprAprAprAprAprAprGprGprGprAprGprUprUprGprAprCprGprUprAprGprAprCprUprGprUprGprCprGprGprAprAprUprGprGprAprUprCprCprAprCprAprUprCprUprAprCprGprAprAprUprUprCp3'
90
29103.68 g/mole
916900 L/(mole·cm)
46.67%
1.09
31.74
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Park et al. "Selection of an Antiviral RNA Aptamer Against Hemagglutinin of the Subtype H5 Avian Influenza Virus." Nucleic Acid Therapeutics, 21(2011): 395-402.
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