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Apta-Index™: Trypanosoma cruzi-Heparan Parasite Receptor (HS6) (ID# 169)

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Trypanosoma cruzi-Heparan Parasite Receptor (HS6) (ID# 169)

Trypanosoma cruzi-Heparan Parasite Receptor (HS6)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
2'-F-RNA Trypanosoma cruzi-Heparan Parasite Receptor Cells 40 nM (reported value) 50 uM RNA containing 20 mM glucose. N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
5'-rApfCpfCprGprAprGpfUpfCpfCprAprGprAprAprGpfCpfUpfUprGpfUprAprGpfUprApfCpfUprApfCpfCprGpfCprAprApfCprGpfUpfUprGprGpfCprGpfUpfUpfCprGprGpfCprGpfUpfUprGprGpfCpfCprGpfCprGpfUpfCprApfUpfCprGpfCpfUprAprGpfCpfCpfUprAprGprApfUprGprGprAprGpfUpfUprGprAprApfUpfUpfCpfUpfCpfCpfCpfUprApfUprAprGpfUprGprAprGpfUpfCprGpfUprApfUpfUprApfCp-3'
107 34422.25 g/mole 1047600.00 L/(mole·cm) 52.34% 0.95 32.86

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Ulrich et al. "In Vitro Selection of RNA Aptamers That Bind to Cell Adhesion Receptors of Trypanosoma cruzi and Inhibit Cell Invasion." The Journal of Biological Chemistry, 277 (2002): 20756-20762.

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