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Apta-Index™: Trypanosoma cruzi-Thrombospondin Parasite Receptor (T6) (ID# 167)

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Trypanosoma cruzi-Thrombospondin Parasite Receptor (T6) (ID# 167)

Trypanosoma cruzi-Thrombospondin Parasite Receptor (T6)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
2'-F-RNA Trypanosoma cruzi-Thrombospondin Parasite Receptor Cells 400 nM (reported value) 50 uM RNA containing 20 mM glucose. N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
5'-rApfCpfCprGprAprGpfUpfCpfCprAprGprAprAprGpfCpfUpfUprGpfUprAprGpfUprApfCpfUpfCprAprApfUprApfCpfUpfCprAprAprGpfCprAprAprGpfCpfCpfCprAprGpfCpfCpfCpfUprApfCpfCprAprApfCpfCpfCpfCprGprGprAprGpfCpfCpfUprAprGprApfUprGprGprAprGpfUpfUprGprAprApfUpfUpfCpfUpfCpfCpfCpfUprApfUprAprGpfUprGprAprGpfUpfCprGpfUprApfUpfUprApfCp-3'
103 33037.62 g/mole 1016600.00 L/(mole·cm) 49.51% 0.98 32.50

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Ulrich et al. "In Vitro Selection of RNA Aptamers That Bind to Cell Adhesion Receptors of Trypanosoma cruzi and Inhibit Cell Invasion." The Journal of Biological Chemistry, 277 (2002): 20756-20762.

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