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Apta-Index™: Zinc (ID# 149)

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Zinc (ID# 149)

Zinc
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
RNA Zinc Small Organic 1.2 mM (reported value) Buffer A (0.4 M NaCl, 20 mM HEPES-Na (pH 7.0), and 1 mM MgCl2) N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
5'-rGprGprGprAprGprAprGprGprAprUprAprCprUprAprCprUprGprUprCprAprUprAprCprGprUprUprAprGprGprCprUprGprUprAprGprGprCprGprAprGprGprUprGprAprAprAprUprGprAprGprCprGprGprUprAprAprUprAprGprCprCprUprCprAprGprCprGprUprAprGprCprAprUprAprUprGprCprAprUprGprAprAprUprUprCprGprAprAprGprCprUprUprCprGprCp-3'
95 30777.60 g/mole 966700.00 L/(mole·cm) 49.47% 1.03 31.84

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Ciesiolka et al., "Selection of an RNA domain that binds Zn2+." Journal of RNA, 1(1995): 538-550.

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