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Apta-Index™: Protein Tyrosine Phosphatase (N71yc16) (ID# 137)

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Protein Tyrosine Phosphatase (N71yc16) (ID# 137)

Protein Tyrosine Phosphatase (N71yc16)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
RNA Protein tyrosine phosphatase (PTPase) Protein 18 nM (reported value) Selection Buffer (20 mM Tris (pH 7.6), 150 mM NaCl, 5 mM MgCl2, 1 mM dithiothreitol; 100 µl final volume) N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
5'-rGprGprGprAprGprAprUprAprCprCprAprGprCprUprUprAprUprUprCprAprAprUprUprCprUprGprGprCprAprAprUprGprGprGprCprUprAprUprCprCprCprAprAprGprUprGprCprUprAprGprGprCprUprUprCprAprGprGprGprAprGprCprGprAprGprGprAprCprCprAprGprAprCprGprAprCprGprUprAprCprCprUprAprAprCprCprCprUprAprAprGprGprUprGprAprGprAprUprAprGprUprAprAprGprUprGprCprAprAprUprCprUp-3'
112 36151.85 g/mole 1126100.00 L/(mole·cm) 50.00% 0.89 32.10

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Bell, S., et al. "RNA Molecules That Bind to and Inhibit the Active Site of a Tyrosine Phosphatase." The Journal of Biological Chemistry, 273(1998):14309-14314.

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