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Apta-Index™: Advanced Glycation End Products (Clone 9) (ID# 128)

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Advanced Glycation End Products (Clone 9) (ID# 128)

Advanced Glycation End Products (Clone 9)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
DNA Advanced Glycation End products (AGE) Protein 1 pM (reported value) N/A N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
5'-dApdGpdCpdTpdCpdApdGpdApdApdTpdGpdGpdApdTpdCpdCpdApdApdApdCpdGpdCpdTpdCpdApdTpdApdApdCpdTpdCpdApdCpdTpdCpdCpdApdTpdApdCpdTpdCpdApdCpdTpdTpdGpdCpdTpdGpdApdTpdTpdCpdGpdCpdCpdApdApdCpdApdApdCpdApdCpdApdCpdCpdCpdTpdTpdApdApdApdCpdApdGpdTpdCpdCpdCpdTpdTpdCpdGpdApdCpdApdTpdGpdApdGpdApdApdTpdTpdCpdGpdGpdCpdCpdGpdGpdApdTpdCp-3'
106 32346.02 g/mole 1004700.00 L/(mole·cm) 48.11% 1.00 32.19

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Higashimoto, Y., et al. "In vitro selection of DNA aptamers that block toxic effects of AGE on cultured retinal pericytes." Microvascular Research, 74 (2007): 65-69.

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