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Apta-Index™: RNase H1 (VI-2) (ID# 115)

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RNase H1 (VI-2) (ID# 115)

RNase H1 (VI-2)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
DNA RNase H1 Protein 11 nM (reported value) Buffer A (30 mM Tris–HCl (pH 8.5), 40 mM ammonium sulfate, 20 mM magnesium chloride, and 0.01% 2-mercaptoethanol) N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
5'-dCpdGpdGpdTpdCpdGpdCpdTpdCpdCpdGpdTpdGpdTpdGpdGpdCpdTpdTpdGpdGpdGpdTpdTpdGpdGpdGpdTpdGpdTpdGpdGpdCpdApdGpdTpdGpdApdCp-3'
39 12149.88 g/mole 356700.00 L/(mole·cm) 66.67% 2.80 34.06

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Pileur, et al. "Selective inhibitory DNA aptamers of the human RNase H1." Nucleic Acids Research, 31 (2003): 5776-5788.

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